Arthritis
Encompasses a group of over 100 different conditions that affect joints and surrounding tissues, resulting in varying degrees of discomfort and functional impairment. Arthritis can impact people of all ages and typically worsens over time.
Diagnosis and Assessment:
Accurate diagnosis of the type of arthritis and a thorough assessment of its severity and impact on the patient’s daily life are essential.
Medications:
Depending on the type and severity of arthritis, the National Institutes of Health (NIH) may recommend various medications. Nonsteroidal anti-inflammatory drugs (NSAIDs) are often used to reduce pain and inflammation. Other options include analgesics (pain relievers), corticosteroids (for short-term relief), disease-modifying antirheumatic drugs (DMARDs), and biologics (for certain types of arthritis).
- Biologic Response Modifiers: Biologics are a class of medications that target specific components of the immune system involved in arthritis. They are typically used for moderate to severe forms of arthritis, such as rheumatoid arthritis or psoriatic arthritis. Examples include etanercept (Enbrel), adalimumab (Humira), and infliximab (Remicade).
- Corticosteroids: Corticosteroids, such as prednisone or prednisolone, may be prescribed to reduce inflammation and manage symptoms of arthritis. They are often used for short-term relief during flares or in combination with other medications.
- Janus Kinase (JAK) Inhibitors: JAK inhibitors are a newer class of medications that target the Janus kinase enzymes involved in the inflammatory response. Examples include tofacitinib (Xeljanz) and baricitinib (Olumiant).
- Interleukin-6 (IL-6) Inhibitors: IL-6 inhibitors, such as tocilizumab (Actemra), specifically target the interleukin-6 pathway and are used for the treatment of certain types of arthritis, including rheumatoid arthritis.
Complementary and Alternative Therapies
Some patients may find relief from arthritis symptoms through complementary and alternative therapies, such as acupuncture, massage, or herbal remedies. While evidence for their effectiveness varies, the MD may discuss these options with the patient and consider them as part of a comprehensive treatment approach.
It’s important to note that the treatment of arthritis should be personalized to each patient’s unique needs and consider any comorbidities or individual factors. An MD, in collaboration with the patient, can create a tailored treatment plan focused on managing
symptoms, slowing disease progression, and promoting longevity.